Дата: Пятница, 14.08.2015, 11:57 | Сообщение # 803
Thyroid hormone drugs are natural or synthetic preparations containing tetraiodothyronine (T4, levothyroxine) sodium or triiodothyronine (T3, liothyronine) sodium or both. T4 and T3 are produced in the human thyroid gland by the iodination and coupling of the amino acid tyrosine. T4 contains four iodine atoms and is formed by the coupling of two molecules of diiodotyrosine (DIT). T3 contains three atoms of iodine and is formed by the coupling of one molecule of DIT with one molecule of monoiodotyrosine (MIT).
Both hormones are stored in the thyroid colloid as thyroglobulin.
Thyroid hormone preparations belong to two categories: (1) natural hormonal preparations derived from animal thyroid, and (2) synthetic preparations. Natural preparations include desiccated thyroid and thyroglobulin. Desiccated thyroid is derived from domesticated animals that are used for food by man (either beef or hog thyroid), and thyroglobulin is derived from thyroid glands of the hog. The United States Pharmacopeia (USP) has standardized the total iodine content of natural preparations. Thyroid USP contains not less than (NLT) 0.17 percent and not more than (NMT) 0.23 percent iodine, and thyroglobulin contains not less than (NLT) 0.7 percent of organically bound iodine. Iodine content is only an indirect indicator of true hormonal biologic activity. Cytomel (liothyronine sodium) (liothyronine sodium) Tablets contain liothyronine (L-triiodothyronine or LT3), a synthetic form of a natural thyroid hormone, and is available as the sodium salt. From http://www.tcsindustry.com - TCS INDUSTRY LTD
Дата: Пятница, 22.01.2016, 03:03 | Сообщение # 804
Moxidectin (Milbemycin B<> - ) kills parasites, so is second-hand instead of the prevention and supervise of heartworm and intestinal worms, and can be originate in treatments prescribed in behalf of animals such as dogs, cats, horses, steers and sheep. Application methods towards moxidectin change not later than treatment, and contain oral, topical, and injectable solutions. Cydectin Spurt On is a barter baptize for a formulation in compensation capitalize on on stock and red deer. Moxidectin is a semisynthetic imitative of nemadectin <> - which is produced past fermentation at near Streptomyces cyano-griseus. This Streptomyces species was discovered in a defile sample from Australia in the fresh 1980s unperturbed by an agronomist working in the direction of the American Cyanamid company. Moxidectin treats and controls some of the most common internal and apparent parasites by way of selectively binding to parasites’ glutamate-gated chloride ion channels. These channels are mandatory to the chore of invertebrate fortitude and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and expiration of the parasite. Studies of moxidectin steer the side effects remodel sooner than animal and may be false beside the upshot’s formulation, application method and dosage. The products are usually recommended by a veterinarian to ensure counterbalance use and application. Herding dogs may be avermectin-sensitive, but avermectin-sensitive dogs can permit paragon doses for heartworm prevention. Moxidectin is apparently unharmed for collie breeds. As a heartworm preventative, moxidectin can be injected at one time every six months under the make name Proheart6, or every 12 months lower than drunk the brand name name Proheart SR 12. Moxidectin is the rationale of a irritant to assess its suitability, as an alternate to ivermectin, to doctor onchocerciasis in humans.<> -
From http://www.fmyykj.com - suzhou pharmaceutical technology co.,ltd.